|Sappington Cemetery State Historic Site|
|Location||Saline, Missouri, United States|
SAPPINGTON CEMETERY STATE HISTORIC SITE Latitude and Longitude:
|Area||4.28 acres (1.73 ha) |
|Elevation||666 ft (203 m) |
|Governing body||Missouri Department of Natural Resources|
|Website||Sappington Cemetery State Historic Site|
Sappington Cemetery State Historic Site is a Missouri state historic site located approximately five miles (8.0 km) southwest of Arrow Rock in Saline County. The cemetery houses the graves of Dr. John Sappington and Missouri Governors Meredith Miles Marmaduke and Claiborne Fox Jackson. 
Dr. John Sappington (1776–1856) was a prominent early physician and businessman in Missouri. He was a proponent of using quinine in the treatment of malaria and was at the time the largest importer of the drug in America.  Dr. Sappington also wrote the first medical book published west of the Mississippi River. 
Sappington and his family were heavily involved in antebellum Missouri Democratic politics. Two of his sons-in-law, Meredith Miles Marmaduke and Claiborne Fox Jackson, became Governors of Missouri. Grandson John Sappington Marmaduke was a noted Confederate General in the American Civil War as well as a Missouri Governor in later years.
Established by Dr. Sappington himself in 1831, the two-acre cemetery holds 111 headstones and grave markers. Sappington Cemetery became a part of the Missouri State Park system in 1967 by act of the Missouri General Assembly.  The site has not been modified for ADA accessibility in order to preserve its historic nature and appearance. No restrooms or other facilities are provided. The site is open sunrise to sunset year-round.
The nearby "Sappington Negro Cemetery" became part of the state historic site in 2014. 
- "Sappington Cemetery". Geographic Names Information System. United States Geological Survey.
- "Sappington Cemetery State Historic Site: Data Sheet" (PDF). Missouri Department of Natural Resources. November 2017. Retrieved May 21, 2018.
- "Sappington Cemetery State Historic Site". Missouri Department of Natural Resources. Retrieved September 9, 2014.
- Glassman, Steve (2008). It Happened on the Santa Fe Trail. Globe Pequot Press. p. 67. ISBN 0762755911.
- "John S. Sappington". Historic Missourians. State Historical Society of Missouri. Retrieved January 10, 2013.
- "Sappington Cemetery State Historic Site: General Information". Missouri Department of Natural Resources. Retrieved September 9, 2014.
- Sappington Cemetery State Historic Site Missouri Department of Natural Resources