|Non-Profit, Private Corporation|
|Founded||Sioux Falls, South Dakota, 1894|
Number of locations
|Iowa, Minnesota, Nebraska, North Dakota, Oklahoma, South Dakota, California, Mexico, Ghana, China, Canada and Germany |
Number of employees
|28,000+ (2018) |
|Footnotes / references|
Key People 
Sanford Health is a non-profit, integrated health care delivery system, with its headquarters in Sioux Falls, South Dakota, with additional offices in Fargo and Bismarck, North Dakota, and Bemidji, Minnesota.
- 1 History
- 2 Centers of Excellence
- 3 World Clinics
- 4 Facilities
- 5 References
- 6 External links
Sanford Health has its roots in the Dakotas at the beginning of the 20th century with Sioux Falls Hospital opening in Sioux Falls in 1894, and St. Luke's Hospital opening in Fargo in 1908. Over the next 80 years, both hospitals grew in size and influence, becoming integrated hospital-clinic systems known as Sioux Valley Health System and MeritCare Health System. The Sioux Valley Health System was renamed Sanford Health in 2007 after Denny Sanford's $400 million gift to the organization.   On November 2, 2009, MeritCare was taken over by Sanford.    Additional mergers with North Country Regional Health in Bemidji, Minnesota,  and Medcenter One Health Systems followed in 2011 and 2012. 
1917: Sioux Falls Lutheran Hospital's Training School gains accreditation
1919: Sioux Falls Clinic building completed; eight doctors opened their offices in this building
1925: Board decided to merge with the Bethany Association
Dec. 1, 1925: Reverend Fonkalsrud begins as director of the Sioux Valley Lutheran Hospital Association
Feb. 26, 1926: Voted to drop Lutheran from the name of the hospital; institution known as Sioux Valley Hospital from that point on
Mar. 15, 1927: Sioux Valley Hospital enters into agreement with city of Sioux Falls to provide a qualified nurse to care for patients at the Detention Hospital of the city
Oct. 15, 1928: Date for opening the appeal for the Sioux Valley New Hospital Fund; total of $225,000 raised by Dec. 1928
Feb. 8, 1929: Land purchased in the Hayward Addition
Mar. 1929: Actual construction began
1930: New hospital building completed
July 11, 1930: Patients moved from old hospital building to new facility
July 12, 1920: First baby born at new hospital; named Spencer Valere Hollis Brende by the nurses (initials chosen for Sioux Valley Health)
1931: Old Sioux Falls Lutheran Hospital building moved to 20th St. and Covell Ave.
1935: Ann Haugan Berdahl hired as first full-time employee for nursing education
Nov. 16, 1943: Contract to build the first addition to the 1930 building awarded
Oct. 12, 1947: Sioux Valley Hospital approved by the American Medical Association
Aug. 6, 1956: Post-Anesthesia Recovery Unit opens
Aug. 30, 1959: Neon Lorraine Cross was lit, changing Sioux Falls skyline
Mar. 26, 1961: Ann Berdahl Hall dedicated during cornerstone-laying ceremony
Nov. 7, 1961: Lyle Schroeder named hospital administrator by Board of Trustees
July 1, 1962: Construction began on the west wing, nicknamed "West Side Story"
Feb. 9, 1964: Third floor of new wing opened
Mar. 26, 1964: Pediatric unit opened
May 15, 1964: Emergency and outpatient areas of new west wing opened
Jan. 2, 1965: Sioux Valley Hospital opened a "special care unit"
Aug. 1968: Sioux Valley Hospital bought three-fourths of the block between Euclid and Grange Avenues and between 17th and 18th Streets
Nov. 1968: SVH made a request of the city to vacate Euclid Ave. between 18th and 20th Streets
Oct. 28, 1969: Groundbreaking ceremonies held
Aug. 2, 1971: Kidney dialysis unit opened
Apr. 29, 1973: 1000 and 2000 floors of nursing tower opened; patients moved into towers May 9, 1973
July 1, 1973: Family practice residency began
Feb. 1974: 4 North nursing unit reopened as urology unit
Sept. 17, 1974: Intensive care nursery opened
Jan. 13, 1975: South Dakota's first medical museum opened at Sioux Valley Hospital
Apr. 1, 1975: Department of Pastoral Care at SVH began with arrival of Chaplain Charles Sommers
May 15, 1976: Expansion plan for SVH announced
Jan. 1, 1977: First patient by the new air transport program
Sept. 18, 1978: Same-Day Surgery Unit opened on 2 North
Summer 1979: SVH established intensive care unit for children
Aug. 19, 1979: EKG Department and Cardiac Catheterization Lab merged to form the Department of Cardiovascular Services
Mar. 22, 1983: $12.8 million expansion plan presented to SD Department of Health
Aug. 24, 1983: Cardiac Rehabilitation Exercise Program moved from track in the basement of the Ancillary Building to Carousel Skate
Nov. 1, 1983: Eating Disorders Program began as regional referral program
Jan. 13, 1984: Services in diagnosis and control of chronic or acute pain combined with psychosocial services to provide multidisciplinary approach to treatment of pain; named the Pain Control Clinic
Feb. 1984: Intensive Care Nursery Follow-Up Clinic added
May 1984: Colors of Sioux Valley logo changed from pink and purple to red and blue
July 30, 1984: New ambulance entrance opened
Aug. 1984: Nuclear medicine department received a perfect score and top ratings from the Nuclear Regulatory Commission
May 1985: Director of housekeeping, Florence Parker, notified that her department ranked first nationally in the housekeeping category of American National Productivity Data Comparison Reporting Systems
Sept. 12, 1985: Lyle Schroeder announced Center for Elder Health and Enrichment
Aug. 1988: Groundbreaking ceremony for new wellness center
Jan. 2, 1989: Sioux Valley Hospital became smoke-free institution
Aug. 16, 1989: Wellness Center opened at final cost of $5.7 million
Apr. 18, 1990: Grand opening for new Rehab Unit
Aug. 7–8, 1990: Intensive Care East-Cardiovascular Surgical Unit opened doors
Dec. 1990: Heart Center opened
Oct. 1991: Sioux Valley Hospital Outpatient Rehabilitation Center and Family Practice Physicians' new clinic opened
Dec. 1991: SVH Intensive Air awarded 1991 Air Medical Safety Award from the MBB Helicopter Corporation; received in recognition of 1,000 consecutive accident-free EMS helicopter missions
Mar. 1992: $27 million expansion plan announced
Apr. 1992: SVH chosen as one of four sites in nation to test Holmium laser designed to correct farsightedness or astigmatism of the eye; Dr. Vance Thompson involved in this clinical research for what is now LASIK surgery
June 1992: Center for Rural Health Services announced
Oct. 1992: Breast Health Institute opened
Apr. 22, 2993: Excimer laser used to correct nearsightedness by Dr. Vance Thompson, director of refractive surgery
Aug. 1993: Women's Pavilion introduced
Fall 1993: 5000 and 6000 floors of nursing towers completed; provided new facilities and a new type of delivery system called "patient-focused care"
Sept. 24, 1993: SVH began to serve as a site for interactive video teleconferencing on the Rural Development Telecommunications Network; purpose to link institutions and cities around the state for sharing information
July 1994: Construction began on second Hospice Cottage
1994: Centennial year: Sioux Valley Hospital grows to become a 476-bed medical center with 3,000 support and professional staff members, serving 20,000 patients a year
1994: Sioux Valley Physician Alliance starts up with 40 physicians representing primary care groups; specialty practices and other physicians join over the next 5 years, growing the practice group to 120 physicians
1996: Ranked the region's best-performing hospital in U.S. News & World Report's list of "America's Best Hospitals"
1996: Kelby Krabbenhoft hired as new CEO of Sioux Valley Hospital. He was selected by the board for his experience with the integrated care model and his vision for carrying it out.
1997: SVH reorganized under the name Sioux Valley Hospitals and Health System. Under Krabbenhoft, the system became committed to integrated care.
1998: Through Krabbenhoft's leadership, the initial Sanford Research organization is formed with a commitment of $1 million per year for scientific discovery to enhance patient care.
Jan. 1998: Sanford Health Plan is up and running. The plan was designed and launched by Ruth Krystopolski, who runs it today.
Apr. 1, 1998: First commercial plan was sold to Sioux Falls Christian School
1999: Krabbenhoft and Becky Nelson form a plan for five "Centers of Excellence" to help lead Sioux Valley Hospitals and Health System's future development; The centers include Heart, Cancer, Women's, Children's and Ortho/Neuro/Trauma
2000: Sioux Valley Hospitals and Health System and the University of South Dakota establish an agreement for advancing medical education and the role of the hospital. Sioux Valley Hospital adds USD Medical Center to its name.
2001: Sioux Valley Physician Group merges with Central Plains Clinic. Addition of the clinic helps SVH and Health System reach its goal of becoming a fully integrated health system.
2003: Two major multimillion expansions occur; the NORTH Center provides spaces for orthopedic surgeons, neurologists, and neurosurgeons, and a $30 million center devoted to cancer treatment also opens.
Mar. 13, 2003: Sioux Valley Hospitals and Health System demonstrates an early indication of what will become a pattern of partnering with other community entities with the announcement of an agreement between the health system and the local YMCA to build a large $8 million wellness center on Sioux Falls's west side.
2005: Kelby Krabbenhoft secures a commitment from Denny Sanford to donate $400 million to launch ambitious initiatives, including curing a devastating disease and establishing clinics around the world.
2006: Expansions include a $55 million surgical center that doubles the operating room area and quadruples the size of the recovery unit
2006: The Boekelheide Neonatal Intensive Care Unit opens, featuring 47 private rooms and state-of-the-art life-saving technology for premature newborns.
Feb. 3, 2007: Denny Sanford's transformational $400 million gift is made public, announcing five children's clinics throughout the U.S., research efforts, and The Sanford Project, an all-out effort to cure an as-yet-undetermined disease; concurrent with the announcement, the health system's name is changed to Sanford Health.
Feb. 4, 2007: Sanford Health puts out a request for proposals to invite applications for the Sanford Children's Clinic program.
Feb. 4, 2007: South Dakota economist Randall Stuefen predicts Denny's $400 million gift will generate thousands of jobs and will drive $1.15 billion in economic development for the area in the next decade.
Feb. 17, 2007: Krabbenhoft says at a meeting with the Argus Leader newspaper editorial board that the previously announced five pediatric care clinics across the U.S. and abroad have now grown into a much more ambitious 20 clinics around the world within a decade.
June 2007: Sanford Health is selected as one of the original National Community Cancer Centers by the National Cancer Institute.
Nov. 18, 2007: Denny pledges $20 million to establish the Sanford Children's Health Research Center, a joint venture of Sanford Health and the Burnham Institute for Medical Research in La Jolla, California.
Apr. 17, 2008: Sanford Project finalists argue their cases to an advisory council. The council agrees that the Sanford Project should tackle type 1 diabetes.
July 10, 2008: Todd and Linda Broin provide their $10 million gift to fund the Sanford Project chair position several weeks after the announcement that type 1 diabetes would be its focus.
2009: MeritCare of Fargo, North Dakota, and Sanford Health merge to form Sanford Health–MeritCare, the nation's largest, rural, not-for-profit health care provider with a presence in 112 communities throughout seven states.
May 2009: Ribbon-cutting ceremony for the Sanford Children's Hospital Castle of Care
May 15, 2009: Sanford Health accelerates research initiatives by purchasing the Hutchinson Technology Campus in Sioux Falls. Purchasing the 300,000 square foot building allows Sanford Health to rapidly expand its multiple research initiatives and also serves as corporate offices in Sioux falls.
Aug. 3, 2009: The first of the Sanford Children's Clinics opens in Duncan, Oklahoma. The 8,000 square foot facility, with the same castle motif used for the Sanford Children's Hospital in Sioux Falls, provides pediatric care for children in the area, some of whom previously had to travel more than an hour to see a pediatrician.
Sept. 2009: Renowned researcher Alex Rabinovitch begins The Sanford Project clinical trials, with the goal of finding a cure for type 1 diabetes. Dr. Rabinovitch's track record of chronic disease research spans decades.
Sept. 10, 2009: Sanford Health breaks ground on the new Sanford Heart Hospital in Sioux Falls
Jan. 29, 2010: Denny Sanford issues a $50 million matching gift challenge benefitting the Burnham Institute for Medical Research to accelerate its research. It is Denny's second gift to Burnham, the first being $20 million in 2007 directed through Sanford Health to create the Sanford Children's Health Research Center at Burnham. With the second gift, the organization is renamed the Sanford-Burnham Medical Research Institute.
June 2010: The Sanford Research Center, home to Sanford Health's expansive research efforts opens in Sioux Falls, in an ultramodern, state-of-the-art facility where dozens of researchers conduct their work.
July 28, 2010: Sanford Health embarks on a partnership with WebMD and The Walt Disney Company to create "fit" an interactive online site to encourage a healthy and active lifestyle for children ages 2–18.
Oct. 13, 2010: Sanford Health researches win a $7 million grant to help address health disparities among American Indians. The grant will help establish a National Center on Minority Health and Health Disparities (NCMHD) Exploratory Center of Excellence.
Mar. 1, 2011: Sanford Health completes a merger with North Country Health Services in Bemidji, MN, integrating hospital and clinic and establishing Sanford Bemidji as a key regional hub in Northern Minnesota.
Mar. 24, 2011: Sanford Health's second Sanford Children's Clinic opens in Oceanside, California, partnering with nearby Rady Children's Hospital to provide comprehensive, community-based care for the roughly 110,000 children that live within 10 miles of the facilities.
Aug. 17, 2011: The Edith Sanford Breast Cancer Initiative, named after Denny's mother, is launched to conduct breast cancer research, foster a grassroots support network, and focus on personalized women's care.
Sept. 15, 2011: Sanford Health partners with the American College of Sports Medicine to create the National Youth Sports Health & Safety Institute, which will advocate for developing and advancing research, education, and policy to enhance the health and safety of children and teens involved in sports and physical activity
2012: Denny is selected for the University of Minnesota Alumni Achievement Award
2012: Denny is named Outstanding International Philanthropist of 2012 by the Association of Fundraising Professionals
Jan. 2012: Sanford Health announces that not only is the Ghana World Clinic now operational, a minimum of three more will be opened in that country before year's end.
Mar. 8, 2012: Sanford Research's Coordination of Rare Diseases at Sanford Program has been selected to join the International Rare Diseases Research Consortium (IRDiRC), an international group formed to work together across the globe to speed up research in the areas of rare disease. The CoRDS program was selected because of the work being done and the financial commitment to rare-disease research.
May 2012: The Sanford Project completes enrollment of 54 patients, ages 11 to 45, who make up the first double-blind clinical trial group of The Sanford Project, investigating a drug that is able to reverse diabetes in animals.
May 12, 2012: Groundbreaking ceremony for the Pentagon, an innovative 160,000 square foot facility that includes nine basketball courts, including professional/college/high school regulation courts for teams of all ages, plus a special "heritage court" of vintage basketball décor. The Pentagon is part of the 162-acre Sanford Sports Complex in Sioux Falls; the Sanford Sports Complex also includes the Sanford Fieldhouse, which holds the headquarters for The National Institute of Athletic Health and Performance.
Apr. 2012: Internationally renowned breast cancer researcher Dr. Brian Leyland-Jones is hired to head up Sanford Health's breast cancer initiatives.
July 2, 2012: Sanford Health completes a merger with Medcenter One in Bismarck, ND. With the addition of Sanford Bismarck, the system reaches into seven states and extends coverage over 220,000 square miles, with 1,200 physicians, 25,000 employees, and facilities in 126 different communities.
July 8, 2012: Sanford Health implements electronic medical records software in its Ghana clinics. EMR software greatly increases the efficiency and quality of patient care but is often unavailable or severely limited in developing countries.
Aug. 1, 2012: Sanford Project researchers reach a critical milestone in a clinical trial testing a combination of two medications to determine if the drugs can help patients with type 1 diabetes keep their blood glucose levels under control with less or no insulin.
Aug. 21, 2012: Sanford Health is awarded a $1.6 million grant to study and combat the unusually high incidence of cervical cancer in American Indian women. The five-year grant will fund research headed up by Subhash Chauhan, PhD, leading a team of seven researchers.
Oct. 1, 2012: The Castle of Care Sanford Children's Clinic opens in Klamath Falls, Oregon
2013: Researchers working with the Edith Sanford Breast Cancer initiative completed first-stage analysis of tissue bank samples from the 175 breast cancer patients participating in this project.
June 2013: Results of the first clinical trial conducted for The Sanford Project, involving 54 patients, are evaluated to establish next steps regarding drugs and drug combinations under investigation to find a cure for type 1 diabetes.
June 2013: Sanford Health is projected to reach 100,000 participants in its health insurance plan that was launched in Apr. 1998.
Fall 2013: The $22 million Sanford Pentagon is set to host year-round basketball tournaments, training camps, and other events as part of the 162-acre Sanford Sports Complex. The National Institute of Athletic Health and Performance will be headquartered at the complex. The grounds house the community's junior football fields and other planned sports venues.
2014: Sanford Imagenetics, a personalized medicine program, is announced with a $125 million gift from Denny Sanford; Imagenetics includes primary care, genetic counseling, and education for targeted treatment using patients’ own DNA.
2016: Sanford performs first adult stem cell therapy, part of an FDA-approved clinical trial to treat shoulder injuries using regenerative medicine.
Apr. 2016: Sanford Health invited to the Vatican Conference on Progress of Regenerative Medicine. Sanford Health and Denny Sanford receive Pontifical Key Innovation Award.
Oct. 2016: Edith Sanford Breast Center opens its doors. The three-story, 48,000 square foot facility is dedicated to integrated breast health services involving education, prevention, research, and the latest in treatment options. It is named for Denny Sanford's mother, who died of breast cancer when he was 4 years old.
2012–2017: Campus expansion continues, including Sanford Cancer Center, Van Demark Building, Ronald McDonald House, Make-A-Wish, and Ava's House (adult and pediatric hospice), as well as Sanford Clinic facilities throughout the Sioux Falls area
July 25, 2017: Sanford Medical Center Fargo opens as a comprehensive regional facility. The $500 million project is the largest in the Midwest and provides hospital and clinic services.
Oct. 2017: Sanford Imagenetics building completed, incorporating internal medicine and genetics to deliver care specific to each patient's DNA
Nov. 2017: The Sanford House, a tribute to Denny Sanford, one of health care's greatest philanthropists, opens on the Sanford Center campus. Mr. Sanford's cumulative contributions to Sanford Health total nearly $1 billion. Sanford House exhibits detail Mr. Sanford's life story and incredible philanthropy to “Improve the Human Condition.”
Dec. 2017: Sanford Health announces the $1 million Sanford Lorraine Cross Award, an award honoring the mavericks of the medical world who have transcended traditional thinking and brought forth a breakthrough that is impacting health care today.
Jan. 2018: The expansion of the World Clinics is announced, with six new clinics opening, one in New Zealand, Ireland, China, Vietnam, Costa Rica, and South Africa
June 2018: Sanford and The Evangelical Lutheran Good Samaritan Society, both Sioux Falls–based organizations, announce the completion of an affiliation agreement with affirmative votes by the Sanford Board of Trustees and the Society Membership; it then goes into FTC review.
Aug. 2018: Sanford and The Evangelical Lutheran Good Samaritan Society clear regulatory review and will proceed with merging the two companies in early 2019
Jan. 2019: Sanford and the Evangelical Lutheran Good Samaritan Society officially merge.
Medcenter One Health Systems was a non-profit American health care provider headquartered in Bismarck, North Dakota. Medcenter One offered nine clinics, three long-term care facilities, and multiple hospital affiliations. Medcenter One was designated as a Level II trauma center. It was bought and merged into Sanford Health in 2012. 
In Nov. 2017, talks were begun to form an affiliation agreement between Sanford and the Good Samaritan Society. After discussions and the formation of synergy teams that strategized how the two organizations could combine, final votes were taken by both parties to the agreement. On Apr. 26, 2018, the Society Board of Directors voted that the Society Membership consider approving the affiliation agreement. On June 21, 2018, the Sanford Board of Trustees voted to approve the affiliation agreement. On June 26, 2018, the Society Membership voted to approve the affiliation agreement. A press conference was held later that day during which Sanford Health President and CEO Kelby Krabbenhoft and Society President and CEO David Horazdovsky signed the affiliation agreement. It was announced that the affiliation would then go into regulatory review with an expected approval date of Jan. 1, 2019. If approved, The Evangelical Lutheran Good Samaritan Society would change its name to The Evangelical Lutheran Good Samaritan Society of Sanford Health. Sanford Health would retain its name. As it happened, the affiliation agreement met the requirements of regulatory review earlier than expected, with an announcement on Aug. 17, 2018. The merger completed January 1, 2019. 
Sanford Health strives to maintain five centers of excellence: cancer, children's, heart, orthopedics/sports medicine, and women's health. These five centers of excellence were envisioned by Kelby Krabbenhoft and Becky Nelson in 1999 to drive the health system's pursuit of excellence in patient care. 
Sanford Cancer attempts to implement the latest technology and innovative research and has a team of experts to deliver levels of care from the first treatment to survivorship and beyond. Three cancer centers are located in Sioux Falls, South Dakota; Fargo, North Dakota; and Bemidji, Minnesota and have developed into referral hubs for cancer treatment throughout the region. The centers participate in clinical trials and research in collaboration with leading cancer institutions, so they can bring emerging technologies and treatment options to Sanford Health's patients.
Sanford Children's team of experts and specialists deliver foundational care that's tailored to children and stays focused on the family. Sanford Children's has over 300 experts providing care in over 35 specialties, and Sanford Health's commitment to local programs and services help inform, educate, and connect kids, families, advocates, researchers, and health care professionals. The children's hospitals and clinics not only offer state-of-the-art technology but an atmosphere designed just for kids. These imaginative themes, along with child life specialists, help put kids at ease by reducing stress and anxiety. The Child Life team implements distraction therapy, medical play, and other coping mechanisms to help children understand what is happening.
Sanford Children's Castle of Care Hospital in Sioux Falls is a vibrant, colorful world where sick and injured children find inspiration, imagination, and play to be as important to healing as Sanford's technology, research, and medicine. Sanford Children's team of pediatric specialists focus on providing clinical services, advocacy, research, and education to advance and ensure every child is provided the latest in care and services.
Sanford Heart's cardiologists and specialists provide advanced cardiac care, surgery, prevention, emergency, and rehabilitation and the latest technology.
Sanford Heart hospital in Sioux Falls, South Dakota, offers highly advanced integrated and personalized care to the region. Services offered include heart screenings to address the risk factors for heart disease before problems develop and cardiac genetic counseling to better personalize screenings and prevent problems before they happen.
Sanford Fargo Heart and Vascular Clinic offers innovative heart and vascular care in Fargo, North Dakota. Cardiologists, cardiac and vascular surgeons, interventional radiologists, internal medicine experts, and other specialists for customized treatment are brought together to meet patients’ needs and lifestyles. Heart and vascular experts provide advanced coordinated care and are there from preventative heart health services and heart screenings to the newest interventions and procedures to individualized follow-up care.
Expert Heart and Vascular Care in Bismarck, North Dakota, provides comprehensive heart health services, including thoracic and vascular surgery. Many of its heart health services were the first in the region. Services include the cardiac catheterization lab, cardiac rehabilitation program, cardiovascular surgery department, pacemaker clinic, and heart failure clinic.
Sanford Health partners with organizations that share their goal of improving heart health. Together, Sanford Health educates, raises research funding, and promotes heart-healthy, active lifestyles. Community partners include the American Heart Association and Take Heart South Dakota.
Robotic surgery has become a new advance in heart health at Sanford. With robotic technology, surgeons are able to operate with greater precision and control than ever before. Even the most complex and delicate heart procedures can be performed with a minimally invasive approach. Robotic surgery delivers exceptional results, including greater comfort, less scarring, shorter recovery time and a faster-than-ever return to daily life.
Sanford Orthopedics & Sports Medicine has various services and specialties to treat sprains, strains, tears, breaks, joint pain and concussions. Their physicians offer years of experience in diagnosis, surgery and nonsurgical treatments.
Their Sports Medicine team is the official sports medicine provider to many high school, university (including NCAA Division I and Division II teams) and professional teams. Sanford Orthopedics & Sports Medicine is the official sports medicine provider for North Dakota State University (NDSU), South Dakota State University (SDSU), the University of South Dakota (USD), and the Sioux Falls Skyforce. They have partnered with USD and Sioux Falls Skyforce for over 15 and 17 years, respectively.
Sanford Women's supports and cares for patients in all aspects from well-woman visits and reproductive medicine to birth control counseling and education on menopause. Patients receive expert care and the chance to form a meaningful and lifelong bond with their care team. Sanford Women's offers OB/GYN services, including prenatal care, well-woman annual pelvic exams, pap tests, birth control, bladder and pelvic prolapse treatment, menopausal care, and minimally invasive surgical procedures for women of all ages. Sanford Health's specialist focus on helping each woman achieve her best health and address issues related to pregnancy, birth, family planning and gynecological concerns. Care is tailored to meet the specific needs of patients and to provide support, advice and the medical expertise needed for a healthy life.
Sanford Women's Edith Sanford Breast Center is focused on the future of breast cancer care and research. A national nonprofit organization established through a generous $100 million gift from Denny Sanford in 2012, Edith Sanford Breast Center, named for his mother, has over 49 locations and 150 providers in South Dakota, North Dakota and Minnesota and is an integrated part of the Sanford Health organization. The team at Edith Sanford Breast Center includes physicians, researchers, nurses and more all working together to accelerate lifesaving discoveries and raise the standard of breast cancer care. Through the use of personalized medicine, Sanford Health is seeking to cover all areas of breast cancer: prevention, early detection, diagnosis, treatment and survivorship. Their mission is to unlock each woman's genetic code to advance treatment and end breast cancer in future generations.
The Sanford World Clinic initiative, which focuses primarily on international pediatric healthcare, began in 2007. Sanford Children's Clinic Duncan in Oklahoma became the first World Clinic that year. 
As of 2017, Sanford operated clinics in China, Ghana, Germany, and Canada. 
In January 2018, it was announced that Sanford would establish World Clinics in Costa Rica, Ireland, New Zealand, South Africa, and Vietnam and expand its presence in China and Ghana. 
Sanford Health is composed of hospitals, clinics, long-term care, managed care, licensed practitioners, a health plan, a foundation, a clinical research center and seven basic research centers. Its geographical reach covers over 200,000 square miles (520,000 km2) in California, Iowa, Minnesota, Nebraska, North Dakota, Oklahoma, and South Dakota.
Sanford promotes good health by creating facilities for the public that encourage exercise and healthy living. The Sanford Fieldhouse, located in Sioux Falls, South Dakota, houses 85,000 square feet of indoor sport fields. There are also batting cages, indoor tracks, and other workout equipment.  The Sanford Pentagon is also in Sioux Falls, and that houses nine basketball courts.  Both of these buildings were designed with sustainability and building efficiency in mind. Sanford Health worked with JLG Architects on both of these buildings.
Sanford Health has many emergency trauma centers located across the Midwest. In Sioux Falls, South Dakota, the Sanford USD Medical Center is a board-certified Level II Trauma Center, along with a Level II Pediatric Trauma center. Sanford also has Level II centers in North Dakota, and Aberdeen, South Dakota. .
In April 2018 Sanford Health's Fargo, ND Medical center was designated as a Level I Adult Trauma Center , the only Level I facility between Minneapolis, Seattle, Omaha, and Denver, and the only one in the Dakotas.
- "Sanford Health "About Us"". Retrieved 21 May 2018.
- "Sanford Health "About Us"". Retrieved 21 May 2018.
- "Sanford Health-MeritCare Leaders". Retrieved 3 March 2010.
- "The Gift". Retrieved 3 February 2007.
- Lindsay Hamilton; ABC News. "Man Gives Away $400 Million to Hospitals". Retrieved 7 March 2007.
- "Sanford and MeritCare Create A New Health System". Retrieved 3 March 2010.
- Patrick Springer; The Fargo Forum. "Sanford Health and MeritCare Complete Merger". Retrieved 3 November 2009.
- "Sanford and MeritCare Create a New Health System". Retrieved 9 November 2009.
- "Two Health Systems Unite in Bemidji". Retrieved 25 February 2011.
- Medcenter One, Sanford Health Complete Merger, Sioux Falls Business Magazine, 5 July 2012
- Rodengen, Jeffrey L. (2013), Improving the Human Condition: The Story of Sanford Health, Ft. Lauderdale: Write Stuff, p. 83
- Sanford Health News, August 17, 2009. "Sanford Children's Clinic Duncan now open". Retrieved 21 May 2018.CS1 maint: Multiple names: authors list ( link)
- "Sanford World Clinic - Providing Health and Healing Around The World". sanfordworldclinic.org. Retrieved 2017-06-13.
- Paul Heinert; Sanford Health News, January 23, 2018. "Sanford Health increases global presence in 7 countries". Retrieved 21 May 2018.CS1 maint: Multiple names: authors list ( link)
- "Find Your Local Trauma Center - American Trauma Society". www.amtrauma.org. Retrieved 2017-09-10.
- "Sanford Health Fargo verified a Level I Adult Trauma Center". www.sanfordhealth.org. Retrieved 2018-11-12.