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Anderson in 2006
|Born||May 13, 1945|
Wahpeton, North Dakota, U.S.
|Alma mater||University of North Dakota, Antelope Valley College|
Anderson is best known for his roles as mailroom supervisor Mr. Gorpley on Perfect Strangers, the lawyer Holland Manners on the first two seasons of Angel, the cardiologist Dr. Jack Kayson on the television series ER, and as dentist Bernard on Lost. He is also known as the assistant manager of the Hotel Royale in Star Trek: The Next Generation episode " The Royale", and as Mike Seaver's adversarial Principal DeWitt on Growing Pains. In addition, he was one of the recurring actors on various episodes of WKRP in Cincinnati, playing various roles, including an immigration officer in the episode "The Americanization of Ivan". Anderson has guest-starred in Season 8 of NCIS as Walter Carmichael, a middle school teacher whose classroom becomes a crime scene when one of his students is kidnapped. 
Anderson married his wife, Barbara Ann Hancock, in 1985. Together, they have twins. Sam holds advanced degrees in Theatre, American Literature and Creative Writing. He is also a member of the Mystery Writers of America.
- From the Earth to the Moon ( HBO miniseries) - Thomas O. Paine, 3rd Administrator of NASA
- CSI: Miami - Season 1 episode 1
- Criminal Minds - Season 4, "House on Fire"
- WKRP in Cincinnati - Played various characters
- St. Elsewhere - Mr. McGrath
- T. J. Hooker - Leo Santee
- Hill Street Blues - Kenny Sterling
- Tales from the Darkside "Bigalow's Last Smoke" - Dr. Synapsis
- Dallas - Inspector Frank Howard
- Magnum, P.I. - Ray Jones
- The Golden Girls - Mr. Meyer
- 21 Jump Street
- Growing Pains - Principal Willis Dewitt
- Perfect Strangers - Mr. Sam Gorpley
- Star Trek: The Next Generation - Assistant Manager in the episode " The Royale"
- Alien Nation - Thomas Edison in the episode "The Game"
- Picket Fences - FBI Agent Donald Morrell
- The Adventures of Brisco County, Jr. - Simon Wolfe in the episode "Brooklyn Dodgers"
- The Pretender - Dr. Curtis Season 2 "Over the Edge"
- The Stand - Whitney Horgan
- Millennium - Agent Jack Pierson
- The X-Files - Leamus in the episode " The Pine Bluff Variant"
- Friends - Dr. Harad
- Ally McBeal - Mark Harrison
- Angel - Holland Manners
- ER - Dr. Jack Kayson
- Married to the Kellys - Bill Kelly
- L.A. Law - D.D.A. Bill Graphia
- Everybody Loves Raymond - Agent Garfield
- Medium - Dr. Elliot Peterson Season 2 "Time out of mind"
- Lost - Bernard Nadler
- Nowhere Man - Memory man in "Through a Lens Darkly"
- Sam Anderson and Mike Chille Variety Hour
- Malcolm in the Middle - Police Commissioner
- Grey's Anatomy - Michael
- Leverage - Henry Retzing
- NCIS - Walter Carmichael Season 8 "Worst Nightmare"
- Hawaii Five-0 - (Season 2)
- Work It - 1 episode
- Men at Work - James Wilson (season 1, episode 9)
- Justified - Lee Paxton (seasons 4 and 5)
- Castle - Principal Duncan (Season 6 "Smells Like Teen Spirit", 2014)
- Chasing Life - Gerald (Season 1 Episode 3 "Blood Cancer Sex Carrots", 2014)
- Scandal (TV series) - Dr. Melvin Feen aka "Sherman" (Season 2 Episode 6 "Spies Like Us", 2012)
- This is Us - Judge Walter Crowder (Season 2, Episode 7 "The Most Disappointed Man", 2017)
- American Woman - Raymond Turner (Season 1, Episode 2 ",Changes and The New Normal", 2018)
- Airplane II: The Sequel - Man in White
- Movers & Shakers - Ray Berg
- La Bamba - Mr. Ludwig
- Critters 2: The Main Course - Mr. Morgan
- I Come in Peace - Mr. Warren
- Memoirs of an Invisible Man (film) - Chairman of the House Committee
- Forrest Gump - Principal Hancock
- Permanent Midnight - Dr. Olsen
- Slackers - Charles Patton
- Hot Shots! Part Deux - General Jones
- Water for Elephants - Mr. Hyde
- Breaking the Girls - Professor Nolan
- Devil's Due - Father Thomas
- Ouija: Origin of Evil - Mr. Browning
- 2019: Nominated for Lead Actor in a Play for the role of Ichabod Banks in the Road Theatre Company production of The Bird and Mr. Banks 
- "Exclusive: Which Lost Castaway Is Crashing onto NCIS?". TVGuide.com. Retrieved September 8, 2010.
- "Ovation Nominees". October 20, 2009.