|Panola County, Texas|
The Panola County Courthouse in Carthage
Location within the U.S. state of Texas
Texas's location within the U.S.
|• Total||821 sq mi (2,126 km2)|
|• Land||802 sq mi (2,077 km2)|
|• Water||20 sq mi (52 km2), 2.4%|
|• ( 2010)||23,796|
|• Density||30/sq mi (10/km2)|
|Time zone||Central: UTC−6/ −5|
Panola County is a county located in the U.S. state of Texas. As of the 2010 census, its population was 23,796.  The county seat is Carthage.  Located in East Texas, the name of the county is derived from a Choctaw word for cotton.
Until 2013, Panola County was one of about 30  entirely dry counties in Texas, which means that the sale of alcohol was restricted or prohibited. In 2013, local options for alcohol sales were added to the November election ballots and passed, permitting the sale of beer and wine in stores and the sale of mixed beverages at restaurants.
Panola County was formed in 1846 from sections of Harrison and Shelby Counties. It was named after a Choctaw/Chickasaw word for cotton.
Jonathon Anderson, Founder of Panola County. Donated approximately 500 acres of land to found Panola County in the 1800s 
According to the U.S. Census Bureau, the county has a total area of 821 square miles (2,130 km2), of which 802 square miles (2,080 km2) is land and 20 square miles (52 km2) (2.4%) is covered by water. 
U.S. Highway 59
- Interstate 369 is currently under construction and will follow the current route of U.S. 59 in most places.
- U.S. Highway 79
- State Highway 43
- State Highway 149
- State Highway 315
- Farm to Market Road 10
- Farm to Market Road 31
- Farm to Market Road 124
- Farm to Market Road 1970
- Harrison County (north)
- Caddo Parish, Louisiana (northeast)
- De Soto Parish, Louisiana (east)
- Shelby County (south)
- Rusk County (west)
|U.S. Decennial Census
1850–2010  2010–2014 
As of the census  of 2000, 22,756 people, 8,821 households, and 6,395 families resided in the county. The population density was 28 people per square mile (11/km²). The 10,524 housing units averaged 13 per square mile (5/km²). The racial makeup of the county was 78.78% White, 17.67% Black or African American, 0.36% Native American, 0.24% Asian, 1.87% from other races, and 1.07% from two or more races. About 3.5% of the population were Hispanic or Latino of any race.
Of the 8,821 households, 32.00% had children under the age of 18 living with them, 57.90% were married couples living together, 11.30% had a female householder with no husband present, and 27.50% were not families; 25.10% of all households were made up of individuals and 12.80% had someone living alone who was 65 years of age or older. The average household size was 2.53 and the average family size was 3.02.
In the county, the population was distributed as 25.20% under the age of 18, 9.20% from 18 to 24, 25.10% from 25 to 44, 24.60% from 45 to 64, and 15.80% who were 65 years of age or older. The median age was 39 years. For every 100 females, there were 92.30 males. For every 100 females age 18 and over, there were 87.10 males.
The median income for a household in the county was $31,909, and for a family was $37,595. Males had a median income of $31,333 versus $19,017 for females. The per capita income for the county was $15,439. About 11.60% of families and 14.10% of the population were below the poverty line, including 16.50% of those under age 18 and 16.10% of those age 65 or over.
These school districts serve Panola County:
- Beckville ISD
- Carthage ISD
- Elysian Fields ISD (mostly in Harrison County)
- Gary ISD
- Joaquin ISD (mostly in Shelby County)
- Tatum ISD (mostly in Rusk County)
- Tenaha ISD (mostly in Shelby County)
Jonathon Anderson, dedicated Memorial on the Carthage, Tx square. Founder of Panola County & notable resident, the Anderson family continues on his legacy within Panola County.
- National Register of Historic Places listings in Panola County, Texas
- Recorded Texas Historic Landmarks in Panola County
- "State & County QuickFacts". United States Census Bureau. Archived from the original on July 16, 2011. Retrieved December 22, 2013.
- "Find a County". National Association of Counties. Retrieved 2011-06-07.
- "TABC Home Page". www.tabc.state.tx.us. Retrieved 2018-07-28.
- Handbook of Texas Online - PANOLA COUNTY
- "2010 Census Gazetteer Files". United States Census Bureau. August 22, 2012. Retrieved May 6, 2015.
- TxDoT, TTC Section E, Detailed Maps 1 & 2, 2007-12-21 Archived 2009-02-07 at the Wayback Machine
- "Population and Housing Unit Estimates". Retrieved June 9, 2017.
- "U.S. Decennial Census". United States Census Bureau. Retrieved May 6, 2015.
- "Texas Almanac: Population History of Counties from 1850–2010" (PDF). Texas Almanac. Retrieved May 6, 2015.
- "American FactFinder". United States Census Bureau. Retrieved 2011-05-14.
- Leip, David. "Dave Leip's Atlas of U.S. Presidential Elections". uselectionatlas.org. Retrieved 2018-07-28.
- Panola County government’s website
- Panola County from the Handbook of Texas Online
- Dry counties in Texas from the TABC