I-220 highlighted in red
|Maintained by MDOT|
|Length||12.01 mi  (19.33 km)|
|South end||I-20 / US 49 in Jackson|
US 80 in
US 49 in Jackson
|North end||I-55 in Ridgeland|
Interstate 220 (I-220) in Mississippi is a loop around Jackson that provides an interstate connection for Interstate 55 and Interstate 20. The northern terminus for the route is in the northern suburb of Ridgeland, at Interstate 55 exit 104. The highway was Mississippi's first Three-digit Interstate, complete by 1981.
This route provides a route for traffic going to and from the western side of the city. It also provides an alternate route for those heading from Interstate 55 south to Interstate 20 west and from I-20 east to I-55 north by avoiding downtown Jackson.
The southern terminus for the route is in western Jackson at Interstate 20, exit 41. The route is about 12 miles (19 km) long. Although control cities of North Jackson and West Jackson are used at the southern and northern termini, respectively, no control cities are used along the interior length of the route (including guide signs at interchanges). Secondary signs at the termini direct drivers to use the route as a shortcut to Memphis and Vicksburg.
I-220 begins at a southern terminus with I-20, and runs concurrently with US 49.  The first interchange northbound, a partial cloverleaf interchange, is with US 80. The freeway continues north, with an interchange at Clinton Boulevard that provides access to Capitol Street and Bullard Street. After curving to the northeast, I-220 intersects Medgar Evers Boulevard, where US 49 departs from the freeway. The highway also intersects Watkins Drive and Hanging Moss Road before ending at I-55. 
Legally, the route of I-220 is defined in Mississippi Code § 65-3-3.
The interstate was first planned in 1971 and was completed by 1981. 
A new interchange opened to traffic on I-220 in 2004. This $13.4 million project completed a diamond interchange constructed at Industrial Drive between the Clinton Boulevard and US 49 north junctions. The project also resulted in the expansion of I-220 from four to six lanes from Clinton Boulevard (Exit 2A/B) northward to Industrial Drive. 
This section needs expansion. You can help by adding to it. (May 2014)
|—||I-20 / US 49 south – Meridian, Hattiesburg, Vicksburg||I-20 exit 41; southern terminus of US 49 concurrency; directional T interchange.|
|1A||US 80 east||Partial cloverleaf interchange|
|1B||US 80 west|
|2A||Capitol Street||Access to I-220 northbound from westbound Bullard Street available|
|3||Industrial Drive||Diamond interchange|
|5A||Medgar Evers Boulevard||Partial cloverleaf interchange|
|5B||US 49 north – Flora, Yazoo City||Northern terminus of US 49 concurrency|
|8||Watkins Drive||Diamond interchange|
|9||Hanging Moss Road|
Highland Colony Parkway
|—||I-55 – Memphis, Grenada, Jackson||I-55 exit 104; northern terminus; tri-stack directional T interchange.|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
- "Route Log and Finder List - Interstate System: Table 2". FHWA. Retrieved 2007-10-03.
- Jackson (PDF) (Map). Mississippi Department of Transportation. Retrieved May 4, 2014.
- Google (March 19, 2012). "Overview Map of Interstate 220 (Mississippi)" (Map). Google Maps. Google. Retrieved March 19, 2012.
- "3-digit Interstates from I-20". Kurumi. February 20, 2005. Retrieved May 4, 2014.[ self-published source]
- "Interstate-Guide: Interstate 220 Mississippi". Retrieved 2017-03-29.[ self-published source]