I-20 highlighted in red
|Maintained by MDOT|
|Length||154.5 mi  (248.6 km)|
|West end||I-20 at Vicksburg|
|East end||I-20 / I-59 at the Alabama line|
|Counties||Warren, Hinds, Rankin, Scott, Newton, Lauderdale|
Interstate 20 traverses the central region of Mississippi, running 154.5 miles from the Mississippi River at Vicksburg eastward, through Jackson, to the Alabama state line about 15 miles (24 km) east of Meridian. Interstate 20 tends to be more winding and narrow through Mississippi than through other states, and the roadway features several extended segments where opposing traffic is not visible due to trees and other vegetation within the unusually wide median.
Between Edwards and Clinton, I-20 uses the original U.S. 80 alignment, except for a short bypass around Bolton.
In Jackson, I-20 briefly merges with Interstate 55 before separating just east of the Pearl River. The old directional interchange at I-55 North and cloverleaf at U.S. Highway 49 South have been combined / replaced with a new interchange which features both loop and/or flyover ramps, plus several C/D lanes providing direct connections for the most heavily traveled routes.
Just west of Meridian, Interstate 59 joins I-20, and the two highways run concurrently through the city and on to Birmingham, Alabama. Throughout the Mississippi portion of this concurrency, I-59's mileage takes over I-20's.
The Mississippi Department of Transportation recently announced plans to reconstruct I-20 through Vicksburg. The project includes the replacement and/or enhancement of all interchanges, additional lanes throughout the city and a new bridge to close a decades-old break in the south frontage road. Environmental studies are ongoing.
This section contains a table that is missing mileposts for one or more junctions.
|Mississippi River||0.0||0.0||I-20 east – Monroe||Continuation into Louisiana|
|Vicksburg Bridge; Louisiana–Mississippi state line|
|Warren||Vicksburg||1A||Washington Street, Warrenton Road|
|1B||US 61 south – Natchez, Baton Rouge||Western end of US 61 overlap|
|1C||Halls Ferry Road|
|4||Clay Street – Vicksburg National Military Park, Downtown Vicksburg||Signed as exits 4A (east) and 4B (west); westbound exit to Clay Street east and eastbound entrance to eastbound I-20 are via exit 5B|
|5A||US 61 north – Rolling Fork, Yazoo City, Memphis||Eastern end of US 61 overlap|
|5B||MS 27 south – Utica||Westbound entrance is via exit 4B|
|Hinds||||19||MS 22 – Flora, Edwards|
|Clinton||34||Natchez Trace Parkway|
|35||US 80 east / Clinton-Raymond Road||Eastern end of US 80 overlap|
|Jackson||40||MS 18 west / Robinson Road – Raymond||Signed as exits 40A (west) and 40B (east) westbound|
|41||I-220 / US 49 north – North Jackson, Yazoo City||Western end of US 49 overlap; I-220 no number signed|
|42||Ellis Avenue||Signed as exits 42A (south) and 42B (north)|
|43||Terry Road||Signed as exits 43A (south) and 43B (north)|
|44||I-55 south / US 51 south / McDowell Road – McComb, New Orleans||Western end of I-55 overlap; I-55 exit 92C|
|45A||Gallatin Street||Eastbound exit is part of exit 45|
|45B||US 51 north (State Street)||Signed as exit 45 eastbound|
|Rankin||Richland||46||I-55 north – Grenada, North Jackson, Memphis||Eastern end of I-55 overlap; I-55 exit 94|
|47||US 49 south – Hattiesburg, Flowood||Eastern end of US 49 overlap; signed as exits 47A (south) and 47B (north) eastbound|
|Pearl||48||MS 468 – Pearl|
|52||MS 475 – Jackson-Evers International Airport|
|Brandon||54||Crossgates Boulevard, Greenfield Road||Former MS 18|
|56||US 80 – Downtown Brandon|
|59||US 80 – East Brandon|
|Pelahatchie||68||MS 43 – Puckett, Pelahatchie|
|Scott||||77||MS 13 – Puckett, Morton|
|||80||MS 481 – Raleigh, Morton|
|Forest||88||MS 35 – Raleigh, Forest|
|Newton||||100||US 80 – Lake, Lawrence|
|Newton||109||MS 15 – Newton, Philadelphia|
|||115||MS 503 – Hickory, Decatur|
|Lauderdale||||129||US 80 west – Lost Gap, Meehan Junction||Western end of US 80 overlap|
|||130||I-59 south – Laurel, New Orleans||Western end of I-59 overlap, north exit 149; no exit number westbound|
|Meridian||150||US 11 south / MS 19 north – Meridian Airport, Philadelphia||Western end of US 11/MS 19 overlap|
|151||Valley Road, 49th Avenue|
|153||MS 145 south / 22nd Avenue – Quitman|
|154||MS 19 south / MS 39 north ( US 11 north / US 80 east) – Butler, De Kalb||Eastern end of US 11/US 80/MS 19 overlap; signed as exits 154A (south) and 154B (north) eastbound|
|156||Jimmy Rodgers Parkway|
|157||US 45 – Quitman, Macon||Signed as exits 157A (south) and 157B (north)|
|||169||Kewanee ( US 11 / US 80)|
|||I-20 east / I-59 north – Birmingham||Continuation into Alabama|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
- "Mississippi Public Roads. Selected Statistics. Extent, Travel, and Designation" (PDF). Mississippi Department of Transportation. 2011. Retrieved 28 April 2013.
- "Interstate 20 Eastbound." Mississippi @ SoutheastRoads.com
- "Interstate 20 Westbound." Mississippi @ Southeast Roads.com
- "I-20 Exits: Mississippi River to I-55"
- "I-20 Exits: I-55 South to I-59 South"