I-2 highlighted in red
|Maintained by TxDOT|
|Length||46.8 mi   (75.3 km)|
|Existed||May 30, 2013–present|
US 83 / Bus. US 83 in Penitas
SH 364 in
SH 107 in Mission
SH 336 in McAllen
I-69C / US 281 in Pharr
|East end||I-69E / US 77 / US 83 in Harlingen|
Interstate 2 (I-2) is an east–west Interstate Highway running through the Lower Rio Grande Valley of South Texas. It begins at the intersection of U.S. Highway 83 (US 83) and Business U.S. Highway 83 (Bus. US 83) in Penitas and heads eastward before terminating at I-69E/ US 77/US 83 in Harlingen. For its entire length, I-2 runs concurrently with US 83. I-2 also parallels Mexican Federal Highway 2 (Fed. 2), another major east–west route that traces the Mexico-U.S. border along the Mexican side of the Rio Grande.
I-2 begins at an at-grade intersection with US 83 and Bus. US 83 in Penitas. The Interstate heads eastward as a four-lane freeway through the Lower Rio Grande Valley. The route curves southeastward around Mission and McAllen to the south, running near McAllen International Airport. The route curves northeastward around Pharr, where it intersects with I-69C/ US 281 north of the city center. Continuing eastward, the route passes by many small cities, roughly paralleling Bus. US 83. The route ends at an interchange with I-69E/ US 77/US 83 in Harlingen.
On April 1, 2013, the Texas Transportation Commission applied to use the I-2 designation on US 83 from Palmview to Harlingen. Approved by the American Association of State Highway and Transportation Officials at their May meeting, this 47-mile-long (76 km) freeway was already constructed as an Interstate-grade limited-access facility. It connects with I-69E at Harlingen;  and likewise with I-69C in the town of Pharr.  The Federal Highway Administration approved the designation on May 24, 2013,  and the Texas Transportation Commission followed suit on May 30, 2013.  This action finalized the designations of not only I-2, but also of the sections of I-69E from Brownsville to Raymondville, I-69C from Pharr north to the end of the US 281 freeway facility near Edinburg, and also I-369 along a short segment of US 59 freeway west of Texarkana, which will be part of the proposed 115-mile (185 km) connector between the main I-69 trunk in Tenaha and Texarkana.  These approvals added over 100 miles (160 km) to the Interstate Highway System in the Rio Grande Valley.  The signage was installed in summer 2013. 
As of June 2013 [update], the cluster consisting of the recently designated portions of I-2, I-69C, and I-69E in the Rio Grande Valley is not connected to the national Interstate network. This situation is slated to be remedied by scheduled projects to complete I-69E along US 77 between Raymondville and Robstown, and to complete the southern end of the previously signed portion of the I-69 corridor connecting with I-37 west of Corpus Christi. Environmental Protection Agency approval for the upgrade of the US 77 alignment to Interstate standards, including bypasses of the towns along the 91-mile (146 km) routing, was obtained through a Finding of No Significant Impact statement issued on July 13, 2012;  [ needs update] 
This section contains a table that is missing mileposts for one or more junctions.
|Hidalgo||Penitas||0.0||0.0||US 83 west||Western terminus|
|Palmview||1.7||2.7||131||FM 492 (Goodwin Road) / Abram Road|
|3.0||4.8||133||SH 364 (La Homa Road) / Bentsen Palm Drive|
Bus. US 83 / Inspiration Road
|6.0||9.7||135||Los Ebanos Road||Westbound direction bridge over the railway under construction as of July 2015|
|6.5||10.5||136||SH 107 north / FM 1016 south (Conway Avenue)|
|7.7||12.4||137||FM 396 (Bryan Road / Anzalduas Highway)|
|138||FM 494 (Shary Road)|
|McAllen||140||FM 2220 (Ware Road)|
|141||Spur 115 (23rd Street) / Main Street – Airport|
|142||SH 336 (10th Street) / Main Street / 2nd Street – Airport|
|143A||McColl Road / 2nd Street||no direct westbound exit (signed at exit 143B)|
|143B||Jackson Avenue / Sam Houston Avenue|
|McAllen– Pharr line||144|
Bus. US 83 / FM 2061 / FM 3362 (Jackson Road)
|Pharr||145||Sugar Road / Polk Avenue|
|146||I-69C north / US 281 – Edinburg, Pharr||signed as exits 146A (south) and 146B (north); I-69C exits 1A-B|
|146C||Frontage Road||extra eastbound exit; other access is at adjacent interchanges|
|Pharr– San Juan line||147A||Veterans Boulevard|
|San Juan||147B||FM 1426 – San Juan|
|149||FM 2557 south (Stewart Road) / Cesar Chavez Road||direct access to FM 2557 eastbound only|
|Alamo||150A||FM 907 (Alamo Road)|
|Donna||152||FM 1423 (Val Verde Road)|
|154||Spur 433 (Main Street)|
|155A||FM 493 (Salinas Boulevard)|
|||155B||Victoria Road / Midway Road|
|Weslaco||157||Westgate Drive / Mile 6 West Road|
|158||FM 88 (Texas Boulevard)|
|159||Airport Drive / Pike Boulevard||serves Mid Valley Airport|
|160||FM 1015 (International Boulevard)|
|Mercedes||161||Spur 31 (Mile 2 West Road)|
|163B||FM 491 (Texas Avenue)|
|164||Mile 1 East Road|
|165||FM 1425 (Mile 2 East Road)|
|166||Mile 3 East Road|
|Cameron||La Feria||167||FM 2556 (Solis Road)||no direct westbound exit (signed at exit 166)|
|168||Rabb Road||no direct eastbound exit (signed at exit 167)|
|169||FM 506 – La Feria, Santa Rosa|
|||170||FM 733 (Kansas City Road) / White Ranch Road|
|Harlingen||171||FM 800 (Bass Boulevard)|
|172||Altas Palmas Road|
|173||FM 3195 (Stuart Place Road)|
Bus. US 83 west ( Spur 54 east) / Lewis Lane
|175||Tyler Avenue ( Spur 206 east) / Dixieland Road / Bass Pro Drive - Downtown Harlingen||Eastbound exit and westbound entrance|
|46.8||75.3||176||I-69E north / US 77 north – Raymondville, Corpus Christi, Airport||eastbound exit and westbound entrance; I-69E exit 26B|
|46.8||75.3||I-69E south / US 77 south / US 83 south – Brownsville|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
- Essex, Allen (May 30, 2013). "State Adds I-69 to Interstate System". Brownsville Herald. Retrieved June 27, 2017.
- Transportation Planning and Programming Division (n.d.). "Interstate Highway No. 2". Highway Designation Files. Texas Department of Transportation. Retrieved September 3, 2013.
- Staff (May 31, 2013). "Interstate 69" (PDF). Texas Department of Transportation. Retrieved June 7, 2013.
- Special Committee on U.S. Route Numbering (May 4, 2013). "Special Committee on US Route Numbering Report to SCOH on May 3, 2013 Meeting" (PDF) (Report). Washington, DC: American Association of State Highway and Transportation Officials. Archived from the original on October 16, 2017. Retrieved May 16, 2013.
- Special Committee on U.S. Route Numbering (November 16, 2012). "SCOH Report from Special Committee on U.S. Route Numbering Annual Meeting" (PDF) (Report). Washington, DC: American Association of State Highway and Transportation Officials. Retrieved December 23, 2012.
- Staff (May 30, 2013). "Interstate 69 Comes to Texarkana and the Valley" (Press release). Alliance for I-69 Texas. Retrieved May 31, 2013.
- Nino, Mark (May 31, 2013). "Texas Transportation Commission Approves Interstate 69 System". Brownsville, TX: KVEO-TV. Archived from the original on October 19, 2013. Retrieved June 27, 2017.
- Taylor, Steve (May 30, 2013). "Over 100 Miles of Valley Highways To Be Designated Interstate". Rio Grande Guardian. McAllen, TX. Retrieved June 1, 2013.
- Janes, Jared (July 15, 2013). "Valley's I-69 signage the latest stop along superhighway dream". The Monitor. Retrieved July 17, 2013.
- Staff (July 13, 2012). "Agency Gives US 77 Upgrades Final Environmental Clearance" (Press release). Alliance for I-69 Texas. Retrieved June 7, 2013.
- Clark, Steve (August 8, 2011). "Interstate Link to Valley Moves Closer to Reality, Official Says". Brownsville Herald. Retrieved June 7, 2013.
- Texas Department of Transportation, plans of proposed highway maintenance contract (1.58 GB ZIP file), December 2014