I-110 highlighted in red
|Maintained by MDOT|
|Length||4.10 mi  (6.60 km)|
|South end||US 90 in Biloxi|
|North end||I-10 / MS 15 / MS 67 in D'Iberville|
Interstate 110 (I-110) is a 4.1-mile (6.6 km) freeway spur route in Biloxi, Mississippi, running south from I-10 to U.S. Highway 90 (US 90). It is one of very few places on the Interstate Highway System utilizing a drawbridge. The southbound control city is Biloxi, with a series of bridges out over the Gulf of Mexico at the southern terminus. There is no northbound control city; the road is marked with trailblazers reading "TO I-10" instead. It ran entirely concurrently with Mississippi Highway 15 (MS 15), until MS 15 was truncated to I-10.
The route of I-110 is defined in Mississippi Code Annotated § 65-3-3.
I-110 begins at an interchange with US 90 on the Gulf of Mexico in Biloxi. The ramps to and from US 90 eastbound pass over the gulf and the beach. From US 90, the ramps from eastbound US 90 and from westbound US 90 merge, and the route heads north as a four-lane freeway through residential and commercial areas, passing over CSX's NO&M Subdivision railroad line. The highway comes to a southbound exit and northbound entrance serving Division Street. Farther north, I-110 comes to a southbound exit and northbound entrance with Bayview Avenue. After this, the freeway crosses the Biloxi Bay on a drawbridge into D'Iberville. Here, the road comes to a diamond interchange with Rodriguez Street and continues north through areas of homes and businesses. I-110 reaches its northern terminus at a cloverleaf interchange with I-10, at which point the road continues north as MS 15/ MS 67.  
This article needs to be updated.(January 2017)
Completed in the late 1980s, it is the latest Interstate to be numbered I-110.
In 2012 Mississippi Department of Transportation (MDOT) officials started a project to extend I-110 past the Sangani Boulevard intersection across the Tchoutacabouffa River back into Biloxi city proper to end at an intersection with Brandon James Drive. The extension would include a new overpass for Sangani Boulevard/Promanade Parkway and a new Interstate-grade intersection between I-110 and Sangani/Promanade. The project was slated to be completed in the middle of 2013.[ needs update]
This section contains a table that is missing mileposts for one or more junctions.
The entire route is in Harrison County.
|Biloxi||0||0.0||1A/1B||US 90 – Gulfport, Keesler AFB, Ocean Springs||Southbound exit and northbound entrance; southern terminus & signed as exits 0A (west, Gulfport, Keesler AFB) & 0B (east, Ocean Springs)|
|1C||Division Street||Southbound exit and northbound entrance|
|1D||Bayview Avenue||Southbound exit and northbound entrance|
MS 15 / MS 67 north
|I-10 exits 46A-B; northbound exit and southbound entrance; northern terminus is signed as exits 4A (east, Pascagoula, Mobile) and 4B (west, Gulfport, New Orleans); roadway continues as MS 15/MS 67|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
- Adderly, Kevin (January 30, 2018). "Table 2: Auxiliary Routes of the Dwight D. Eisenhower National System of Interstate and Defense Highways as of December 31, 2017". Route Log and Finder List. Federal Highway Administration. Retrieved March 30, 2018.
- Mississippi Department of Transportation (2018). Official State Highway Map Mississippi (PDF) (Map). Scale not given. Jackson: Mississippi Department of Transportation. Gulf Coast Area inset. Retrieved March 30, 2018.
- Google (March 23, 2011). "Overview of Interstate 110" (Map). Google Maps. Google. Retrieved March 23, 2011.
|Wikimedia Commons has media related to Interstate 110 (Mississippi).|