I-10 highlighted in red
|Maintained by MDOT|
|Length||77.056 mi  (124.010 km)|
|West end||I-10 at Louisiana state line|
|East end||I-10 at Alabama state line|
|Counties||Hancock, Harrison, Jackson|
Interstate 10 (I-10) a major east–west Interstate Highway in the southern areas of the United States, has a section of about 77 miles (124 km) in Mississippi.
I-10 enters the Gulf Coast area of Mississippi from Louisiana after crossing the East Pearl River. The highway parallels U.S. Route 90 to the north as it runs through the southern parts of the three southernmost counties in the state: Hancock, Harrison and Jackson.
As it enters the state, the divider for I-10 widens shortly after crossing the Pearl River. The eastbound Mississippi Welcome Center is off the highway at Exit 2 (MS 607), and the eastbound truck weigh station can be found just west of Exit 13 (MS 43/603). Shortly after Exit 13, I-10 crosses a bridge over the Jourdan River and enter Diamondback, where the interstate serves as a buffer between the communities and the north shore of Bay of St. Louis, while crossing the Hancock-Harrison county line at the same time. It widens from four to six lanes between the bridge over the Wolf River and Exit 28 (Country Farm Road) northeast of Cuevas.
The highway passes through the northern section of the city of Gulfport, where after the interchange with Exits 34 A-B (US 49), which has outer ramps that also run above a railway line on the west side of US 49, and Bayou Bernard on the east side of the interchange. Additionally, the interchange is north of the flight plan for planes at Gulfport-Biloxi International Airport. Upon crossing the bridge over the Biloxi River the interstate enters the northern section of Biloxi, where after two diamond interchanges, collective-distributor roads can be found on both sides at Exits 46 A thru D. The eastbound exits here are for Diberville Boulevard (Exit 46A), Interstate 110 (southbound Exit 46B), as well as northbound Mississippi Routes 15 and 67. The westbound exits are for Lamey Bridge Road (Exit 46D), northbound MS 15/67 (Exit 46C), and southbound I-110 (Exit 46B). Shortly after the semi-complex interchange, the route crosses the Harrison-Jackson county line. No other interchanges exist within Jackson County until over three miles later at MS 609 (Exit 50), and the road narrows back down to four lanes east of MS 57 (Exit 57) north of Ocean Springs. One last interchange can be found in Gautier west of a pair of rest areas on both sides of the road on the west bank of the long causeway over the Pascagoula River wetlands. A connecting U-Turn for official and emergency vehicles links both rest areas with one another.
East of the Pascagoula wetlands, the road enters the northern section of Moss Point, where two interchanges with MS 513 and MS 63 are in close proximity to one another before I-10 starts to head northeastward. Following a shorter causeway over the Escatawpa River wetlands, I-10 has one last eastbound truck weigh station across the road from the westbound Mississippi Welcome Center, followed by one last interchange, for Franklin Creek Road (Exit 75). The first westbound truck weigh station can be spotted across the road before I-10 finally enters Alabama after trekking 77 miles (124 km) in the Magnolia State.
This section needs expansion. You can help by adding to it. (December 2013)
Interstate 10 was built in 1982 throughout Mississippi. Interstate 10 was originally completed in Alabama and Louisiana before Mississippi completed its portion. I-10 in Alabama routed onto U.S. Route 90 at the state line, which was the default roadway across southern Mississippi before I-10 was completed. Today, US-90 is not directly accessible from the I-10. When coming from Louisiana, I-10 ended at Mississippi Highway 607 (Exit 2). Today, entering Mississippi from Louisiana, the first twelve miles is the NASA John C. Stennis Space Center easement zone. To this day, I-10 displays the control city of Bay St. Louis from New Orleans, Louisiana and Pascagoula from traveling from Mobile, Alabama. 
|Hancock||||0.0||0.0||I-10 west – New Orleans||Continuation into Louisiana|
|||2.8||4.5||2||MS 607 – NASA John C. Stennis Space Center, Waveland|
|||13.7||22.0||13||MS 43 / MS 603 – Bay St. Louis, Kiln, Picayune|
|Harrison||20.7||33.3||20||Kiln Delisle Road|
|||24.7||39.8||24||Firetower Road / Menge Avenue|
|||28.3||45.5||28||Country Farm Road|
|34.2||55.0||34||US 49 – Gulfport, Hattiesburg||Signed as exits 34A (south) and 34B (north)|
|38.0||61.2||38||MS 605 (Lorraine-Cowan Road) – Bernard Bayou Industrial District|
|41.9||67.4||41||Old Mississippi 67 - Woolmarket|
|Biloxi||44.3||71.3||44||Cedar Lake Road – Coast Coliseum|
|46.6||75.0||46A||Galleria Parkway||Eastbound exit and westbound entrance; diverging diamond interchange|
|46B||I-110 south – Biloxi, Keesler AFB||Exits 46B&C joined by collector-distributor lanes|
|46C||MS 15 north / MS 67 north|
|46D||Lamey Bridge Road||Eastbound entrance and westbound exit|
|Jackson||Ocean Springs||49.8||80.1||50||MS 609 south – Ocean Springs|
|||57.5||92.5||57||MS 57 – Vancleave, Gautier, Ocean Springs|
|Gautier||61.4||98.8||61||Gautier Vancleave Road – Gautier, Vancleave|
|Moss Point||68.0||109.4||68||MS 613 – Moss Point, Pascagoula|
|69.0||111.0||69||MS 63 – East Moss Point, East Pascagoula|
|Pascagoula||75.8||122.0||75||Franklin Creek Road|
|||77.0||123.9||I-10 east – Mobile||Continuation into Alabama|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
- "Mississippi Public Roads Selected Statistics" (PDF). Mississippi Department of Transportation. 2008. Archived from the original (PDF) on 2010-12-03. Retrieved 2010-06-03.
- "What's with Pascagoula anyway? – On The Road". www.aaroads.com. Retrieved 2017-03-06.
- Google (2014-07-27). "Overview map of I-10 in Mississippi" (Map). Google Maps. Google. Retrieved 2014-07-27.
- Media related to Interstate 10 in Mississippi at Wikimedia Commons
- Interstate 10 - Mississippi (AARoads.com)