Anathema, in common usage, is something or someone that is detested or shunned. In its other main usage, it is a formal excommunication.    The latter meaning, its ecclesiastical sense, is based on New Testament usage. In the Old Testament, anathema referred either to something (living or inanimate) that was consecrated or to something denounced as evil or accursed and set aside for sacrificial offering. 
Anathema derives from Ancient Greek: ἀνάθεμα,  anáthema, meaning "an offering" or "anything dedicated",  itself derived from the verb ἀνατίθημι, anatíthēmi, meaning "to offer up". In the Old Testament, it referred to both objects consecrated to divine use and those dedicated to destruction in the Lord's name, such as enemies and their weapons during religious wars. Since weapons of the enemy were considered unholy, the meaning became "anything dedicated to evil" or "a curse".
"Anathema" was initially used in its ecclesiastical sense by St. Paul to mean the excommunication of a heretic or an unrepentant excommunicated heretic. By the 6th century, the liturgical meaning evolved again to mean a formal ecclesiastical curse of excommunication and the condemnation of heretical doctrines, the severest form of separation from the Christian church issued against a heretic or group of heretics by a Pope or other church official.  
- "It's no wonder then, that Paul calls down God's curse, God's anathema, His ban on those behind their potential defection from Christ." 
- "He shrank from the venerable saint as if to avoid an anathema." 
- "In 1054, an anathema was issued by Rome against the Eastern Patriarch who then issued another one against the cardinal who delivered it." 
In 1526, the word "anathema" appeared in modern English for the first time and was used in the sense of "something accursed". The "consecrated object" meaning was also adopted a short time later, but is no longer widely used.  Its most common modern usage is in secular contexts  where it is used to mean something or someone that is detested or shunned. 
The Old Testament applied the word to anything set aside for sacrifice, and thus banned from profane use and dedicated to destruction—as, in the case of religious wars, the enemy and their cities and possessions. The New Testament uses the word to mean a curse and forced expulsion of someone from the Christian community. 
The Greek word ἀνάθεμα (anathema), meaning something offered to a divinity, appeared in the translation of the Jewish Bible known as the Septuagint to render the Hebrew word חרם ( herem), and appears in verses such as Leviticus 27:28 to refer to things that are offered to God and so banned for common (non-religious) use. The Hebrew word was also used for what was devoted, by virtue of a simple vow, not to the Lord, but to the priest.  In postexilic Judaism, the meaning of the word changed to an expression of God's displeasure with all persons, Jew or pagan, who do not subordinate their personal conduct and tendencies to the discipline of the theocracy, and must be purged from the community—thus making anathema an instrument of synagogal discipline. 
The noun ἀνάθεμα (anathema) occurs in the Greek New Testament six times.  Its meaning in the New Testament is disfavour of God, a meaning that, according to Vine's Complete Expository Dictionary of Old Testament and New Testament Words, applies in Acts 23:14 to the sentence of disfavour, and in the other instances to the object of God's disfavour. 
Since the time of the apostles, the term 'anathema' has come to mean a form of extreme religious sanction, known as excommunication. The earliest recorded instance of the form is in the Council of Elvira (c. 306), and thereafter it became the common method of cutting off heretics; for example, the Synod of Gangra (c. 340) pronounced that Manicheanism was anathema. Cyril of Alexandria issued twelve anathemas against Nestorius in 431. In the fifth century, a formal distinction between anathema and "minor" excommunication evolved, where "minor" excommunication entailed cutting off a person or group from the rite of Eucharist and attendance at worship, while anathema meant a complete separation of the subject from the Church.
The Orthodox Church distinguishes between "separation from the communion of the Church" (excommunication) and other epitemia (penances) laid on a person, and anathema. While undergoing epitemia, the person remains an Orthodox Christian, even though their participation in the mystical life of the church is restricted; but those given over to anathema are considered completely torn from the Church until they repent.  Epitemia, or excommunication, is normally limited to a specified period of time—though it always depends on the repentance of the one penanced. The lifting of anathema, however, depends solely on the repentance of the one condemned. The two causes for which a person may be anathematized are heresy and schism. Anathematization is only a last resort, and must always be preceded by pastoral attempts to reason with the offender and bring about their restoration.
For the Orthodox, anathema is not final damnation. God alone is the judge of the living and the dead, and up until the moment of death repentance is always possible. The purpose of public anathema is twofold: to warn the one condemned and bring about his repentance, and to warn others away from his error. Everything is done for the purpose of the salvation of souls.
On the First Sunday of Great Lent—the "Sunday of Orthodoxy"—the church celebrates the Rite of Orthodoxy, at which anathemas are pronounced against numerous heresies. This rite commemorates the end of Iconoclasm—the last great heresy to trouble the church (all subsequent heresies—so far—merely being restatements in one form or another of previous errors)—at the Council of Constantinople in 842. The Synodicon, or decree, of the council was publicly proclaimed on this day, including an anathema against not only Iconoclasm but also of previous heresies. The Synodicon continues to be proclaimed annually, together with additional prayers and petitions in cathedrals and major monasteries throughout the Eastern Orthodox Churches. During the rite (which is also known as the "Triumph of Orthodoxy"), lections are read from Romans 16:17-20, which directs the church to "...mark them which cause divisions and offenses contrary to the doctrine you have learned, and avoid them. For they … by good words and fair speeches deceive the hearts of the simple," and Matthew 18:10-18, which recounts the parable of the Good Shepherd, and provides the procedure to follow in dealing with those who err:
"… if thy brother shall trespass against thee, go and tell him his fault between thee and him alone: if he shall hear thee, thou hast gained thy brother. But if he will not hear thee, then take with thee one or two more, that in the mouth of two or three witnesses every word may be established. And if he shall neglect to hear them, tell it unto the church: but if he shall neglect to hear the church, let him be unto thee as a heathen man and a publican. Verily I say unto you, whatever ye shall bind on earth shall be bound in heaven; and whatsoever ye shall loose on earth shall be loosed in heaven."
After an ektenia (litany), during which petitions are offered that God will have mercy on those who err and bring them back to the truth, and that he will "make hatred, enmity, strife, vengeance, falsehood and all other abominations to cease, and cause true love to reign in our hearts…", the bishop (or abbot) says a prayer during which he beseeches God to: "look down now upon Thy Church, and behold how that, though we have joyously received the Gospel of salvation, we are but stony ground.  For the thorns  of vanity and the tares  of the passions make it to bear but little fruit in certain places and none in others, and with the increase in iniquity, some, opposing the truth of Thy Gospel by heresy, and others by schism, do fall away from Thy dignity, and rejecting Thy grace, the subject themselves to the judgment of Thy most holy word. O most merciful and almighty Lord … be merciful unto us; strengthen us in the right Faith by Thy power, and with Thy divine light illumine the eyes of those in error, that they may come to know Thy truth. Soften the hardness of their hearts and open their ears, that they may hear Thy voice and turn to Thee, our Saviour. O Lord, set aside their division and correct their life, which doth not accord with Christian piety. … Endue the pastors of Thy Church with holy zeal, and so direct their care for the salvation and conversion of those in error with the spirit of the Gospel that, guided by Thee, we may all attain to that place where is the perfect faith, fulfillment of hope, and true love …." The protodeacon then proclaims the Synodicon, anathematizing various heresies and lauding those who have remained constant in the dogma and Holy Tradition of the Church.
In the dogmatic canons of all the ecumenical councils recognized by the Catholic Church, the word "anathema" signifies exclusion from the society of the faithful because of heresy.   Documents of the 9th and 12th centuries distinguish anathema from excommunication, a distinction later clarified by using the term "major excommunication" for exclusion from the society of the faithful, and "minor excommunication" for ordinary excommunication or exclusion from reception of the sacraments. 
Although in the canons of ecumenical councils the word "anathema" continued to be used to mean exclusion for heresy from the society of the faithful, the word was also used to signify a major excommunication inflicted with particular solemnity. Anathema in this sense was a major excommunication pronounced with the ceremonies described in the article bell, book, and candle, which were reserved for the gravest crimes. 
The 1917 Roman Code of Canon Law abandoned the distinction between major and minor excommunication (which continues in use among the Eastern Catholic Churches)  and abolished all penalties of whatever kind envisaged in previous canonical legislation but not included in the Code.  It defined excommunication as exclusion from the communion of the faithful and said that excommunication "is also called anathema, especially if inflicted with the solemnities described in the Pontificale Romanum." 
The 1983 Code of Canon Law, which is now in force, does not contain the word "anathema",  and the Pontificale Romanum, as revised after the Second Vatican Council, no longer mentions any particular solemnities associated with the infliction of excommunication.
- Christian excommunication
- Mark and Avoid
- Bell, Book, and Candle
- "Anathema", Grammarist, retrieved September 22, 2016
- "Anathema", English Oxford Living Dictionaries, Oxford University Press, retrieved September 22, 2016
- "Anathema", Merriam-Webster's Learner's Dictionary, retrieved September 22, 2016
- Encyclopædia Britannica: "anathema (religion)"
- Liddell, Henry George; Robert, Scott. "ἀνάθεμα". A Greek-English Lexicon. Retrieved January 9, 2017.
- Jewish Encyclopedia: "Ban"
- Jewish Encyclopedia: "Anathema (Greek 'Aνάθημα; Hebrew חרם; Aramaic חרמא)"
- in 1 Cor 12:3; 16:22; Gal 1:8,9; Rom 9:3; Acts 23:14
- Vine's Complete Expository Dictionary of Old and New Testament Words (Thomas Nelson 1996 ISBN 978-1-41858585-3), s.v. Curse, Cursing (Noun and Verb), Cursed, Accursed
- St. John Maximovitch, "The Word 'Anathema' and its Meaning", Orthodox Life, vol 27, Mar-April 1977, pp. 18-19
- Cf. Matthew 13:5, etc.
- Cf. Matthew 13:7, etc.
- Cf. Matthew 13:25-40
- Joseph Gignac, "Anathema" in Catholic Encyclopedia (New York 1907)
- Jimmy Akin, "Anathema Sit"
- Code of Canons of the Eastern Churches, canons 1431, 1434
- 1917 Code of Canon Law, canon 6, 5°
- 1917 Code of Canon Law, canon 2257
- Code of Canon Law alphabetical index
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- "Anathema" from Catholic Answers
- "Anathema" in New Advent Catholic Encyclopedia
- Anathema sit in Everything2
- St. Paul's Anathema Esto in Galatians One by Gerald O. Hoenecke
- Christian Cyclopedia article on Anathema
- The Word "Anathema" and its Meaning Eastern Orthodox view by St. John Maximovitch
- What is Anathema by Theophan the Recluse
- The Sunday of Orthodoxy